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von Willebrand Factor

A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND DISEASES is due to the deficiency of this factor.
Also Known As:
Factor VIIIR-Ag; Factor VIIIR-RCo; Plasma Factor VIII Complex; Ristocetin Cofactor; Ristocetin-Willebrand Factor; von Willebrand Protein; Factor VIII Related Antigen; Factor VIIIR Ag; Factor VIIIR RCo; Ristocetin Willebrand Factor; Factor VIII-Related Antigen
Networked: 6708 relevant articles (121 outcomes, 600 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Lip, Gregory Y H: 51 articles (01/2018 - 07/2002)
2. Budde, Ulrich: 49 articles (10/2022 - 04/2002)
3. Favaloro, Emmanuel J: 48 articles (11/2022 - 04/2002)
4. Leebeek, Frank W G: 46 articles (09/2022 - 02/2004)
5. Lenting, Peter J: 39 articles (08/2022 - 03/2004)
6. Federici, Augusto B: 39 articles (08/2022 - 02/2002)
7. Blann, A D: 38 articles (01/2022 - 02/2000)
8. Castaman, Giancarlo: 37 articles (08/2022 - 01/2002)
9. Matsumoto, Masanori: 35 articles (04/2022 - 02/2003)
10. Vanhoorelbeke, Karen: 35 articles (01/2022 - 04/2002)

Related Diseases

1. von Willebrand Diseases (von Willebrand's Disease)
2. Hemorrhage
3. Thrombosis (Thrombus)
4. Hemophilia A (Haemophilia)
5. Thrombotic Thrombocytopenic Purpura

Related Drugs and Biologics

1. Factor VIII (Coagulation Factor VIII)
2. Antigens
3. von Willebrand Factor
4. Collagen
5. Proteins (Proteins, Gene)
6. thiamine triphosphorate (TTP)
7. Deamino Arginine Vasopressin (Desmopressin)
8. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
9. C-Reactive Protein
10. Tissue Plasminogen Activator (Alteplase)

Related Therapies and Procedures

1. Therapeutics
2. Plasma Exchange
3. Heart-Assist Devices
4. Transcatheter Aortic Valve Replacement
5. Prostheses and Implants (Prosthesis)