|1.||Yang, Dawei: 1 article (07/2015)|
|2.||Wang, Peng: 1 article (07/2015)|
|3.||Ren, Xiaoping: 1 article (07/2015)|
|4.||Cai, Li: 1 article (01/2013)|
|5.||Bai, Yuxian: 1 article (01/2013)|
|6.||Dong, Guanglu: 1 article (01/2013)|
|7.||Zhang, Tingting: 1 article (01/2013)|
|8.||Yu, Hongyang: 1 article (01/2013)|
|9.||Liu, Ying: 1 article (01/2011)|
|10.||Nie, Yingkun: 1 article (01/2011)|
|2.||Breast Neoplasms (Breast Cancer)
01/01/2013 - "In this study, the anticancer activity of chamaejasmine was characterized in the human breast cancer cell line, MDA-MB-231. "
01/01/2013 - "Our findings suggested that chamaejasmine could be explored as a preventive and perhaps as a chemotherapeutic agent in the management of breast cancer."
01/01/2013 - "Chamaejasmine arrests cell cycle, induces apoptosis and inhibits nuclear NF-κB translocation in the human breast cancer cell line MDA-MB-231."
01/01/2011 - "In vivo, chamaejasmine intake through gavage resulted in inactivation of Akt and induction of apoptosis in HEp-2 tumors. "
01/01/2011 - "In this work, the anticancer activity of chamaejasmine was studied by evaluating its in vitro cytotoxicity against several human cancer cell lines (MCF-7, A549, SGC-7901, HCT-8, HO-4980, Hela, HepG2, PC-3, LNCap, Vero and MDCK) using the MTT assay. "
07/01/2015 - "Except its potent pain-relieving efficacy as reported, chamaejasmine also exerted its anti-tumor activity in several tumor models. "
07/01/2015 - "The results of p53 shRNA experiment further demonstrated that p53 knockdown severely impaired the sensitivity of tested cells to chamaejasmine, implicating the important role of p53 played in chamaejasmine's anti-tumor activity. "
01/01/2011 - "Results presented here suggest that chamaejasmine possesses anti-cancer properties relating to β-tubulin depolymerization inhibition, and therefore is a potential source of anticancer leads for the pharmaceutical industry."
|4.||Osteosarcoma (Osteogenic Sarcoma)
07/01/2015 - "Apoptosis induced by chamaejasmine in human osteosarcoma cells through p53 pathway."
07/01/2015 - "Here, we reported that chamaejasmine had a profound anti-proliferative effect on human osteosarcoma cells in a concentration-dependent and time-dependent manner, which was associated with an increase of p21 and bax and a decrease of bcl-2 and consequently increased caspase-3 activity. "
07/01/2015 - "In conclusion, results showed chamaejasmine induced apoptosis in MG63 cells and could be a candidate drug for osteosarcoma cancer chemoprevention."
|1.||Caspase 3 (Caspase-3)
|2.||Small Interfering RNA (siRNA)