HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

calcineurin phosphatase

Networked: 22 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Esterases: 1574
      - Phosphoric Monoester Hydrolases: 7477
        calcineurin phosphatase: 22

Experts

1.	Abboud, Hanna E: 2 articles (06/2004 - 01/2003)
2.	Barnes, Jeffrey L: 2 articles (06/2004 - 01/2003)
3.	Gooch, Jennifer L: 2 articles (06/2004 - 01/2003)
4.	Chen, Hong: 1 article (01/2022)
5.	Chen, Hui: 1 article (01/2022)
6.	Chen, Jie: 1 article (01/2022)
7.	Cheng, Lan: 1 article (01/2022)
8.	Hong, Huiwu: 1 article (01/2022)
9.	Lin, Pengcheng: 1 article (01/2022)
10.	Maboh, Rene Nfornah: 1 article (01/2022)

Related Diseases

1.	Caliciviridae Infections 11/01/2017 - "The results from this study demonstrate that calcineurin phosphatase activity and IMPDH guanine synthase activity are crucial in sustaining norovirus infection; thus, they can be therapeutically targeted. "
2.	Cardiomegaly (Heart Hypertrophy) 10/01/2004 - "To study a possible involvement of calcineurin and its downstream pathway in development of cardiac hypertrophy in this transgenic rat model we measured the protein expression of marker proteins of the calcineurin cascade (calcineurin, NFAT-3, GATA-4) and calcineurin phosphatase activity and GATA-4 DNA binding in TGR ( n=10) compared to age-matched Sprague-Dawley rats ( n=10). "
3.	Amyloid Plaque 03/01/1995 - "Calcineurin (phosphatase 2B) is present in neurons containing neurofibrillary tangles and in a subset of senile plaques in Alzheimer's disease." 01/01/2001 - "The decrease in nickel-stimulated calcineurin phosphatase activity in frontal lobe correlated with the neurofibrillary tangle pathology (total cell homogenate, r = -0.77, P < 0.05; P2 fraction, r = -0.76, P < 0.02), but not with diffuse or neuritic plaques. "
4.	Down Syndrome (Down's Syndrome) 11/06/2015 - "Regulator of calcineurin (RCAN) is a calcineurin-interacting protein that inhibits calcineurin phosphatase when overexpressed, often upregulated under neuropathological conditions with impaired learning and memory processes, such as Down syndrome or Alzheimer's disease. " 12/14/2015 - "We show that excess regulator of calcineurin 1 (RCAN1), an endogenous inhibitor of the calcineurin phosphatase that is triplicated in Down syndrome, impairs neurotrophic support of sympathetic neurons by inhibiting endocytosis of the nerve growth factor (NGF) receptor, TrkA. "
5.	Diabetic Nephropathies (Diabetic Nephropathy) 06/01/2004 - "Aquaporin 2 (AQP2), a putative substrate of calcineurin phosphatase in the kidney, is also involved in diabetic nephropathy. " 05/15/2009 - "In contrast, calcineurin phosphatase inhibition through CsA did not ameliorate any of the features of diabetic nephropathy compared with placebo treatment but slightly aggravated glomerular fibrosis without affecting transforming growth factor-beta1/2 or vascular endothelial growth factor. "

Related Drugs and Biologics

1.	Calcineurin
2.	Proteins (Proteins, Gene)
3.	Guanine
4.	DNA (Deoxyribonucleic Acid)
5.	Cyclosporine (Ciclosporin)
6.	Calcium Ionophores
7.	Aquaporin 2
8.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
9.	Nerve Growth Factor (NGF)
10.	Nerve Growth Factor Receptor (Nerve Growth Factor Receptor, Low Affinity)