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coniferaldehyde

from aqueous extract of Senra incana

Also Known As:

4-HM-CA; 4-hydroxy-3-methoxycinnamaldehyde; coniferaldehyde, (E)-isomer; coniferyl aldehyde; coniferylaldehyde; trans-coniferyl aldehyde

Networked: 10 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Aldehydes: 2153
  - Acrolein: 795
    - coniferaldehyde: 10

Experts

1.	Avula, Vennela: 1 article (06/2021)
2.	Clark, Jeliyah: 1 article (06/2021)
3.	Eaves, Lauren A: 1 article (06/2021)
4.	Gilmour, M Ian: 1 article (06/2021)
5.	Jaspers, Ilona: 1 article (06/2021)
6.	Kim, Yong Ho: 1 article (06/2021)
7.	Niehoff, Nicole M: 1 article (06/2021)
8.	Rager, Julia E: 1 article (06/2021)
9.	Gu, Yanhong: 1 article (01/2021)
10.	He, Yichun: 1 article (01/2021)

Related Diseases

1.	Non-alcoholic Fatty Liver Disease 11/01/2020 - "Therefore, our findings provide new evidence in support of that supplementation with coniferaldehyde or food rich in coniferaldehyde might be considered as a viable dietary intervention strategy for preventing and treating nonalcoholic fatty liver disease." 11/01/2020 - "PRACTICAL APPLICATION: In this study, coniferaldehyde appeared to be effective in ameliorating hepatic lipid and glucose metabolism disorders in nonalcoholic fatty liver disease by reducing the levels of intracellular triglyceride and total cholesterol and enhancing glucose uptake and intracellular glycogen content via the LKB1/AMPK signaling pathway in vitro. "
2.	Glucose Metabolism Disorders 11/01/2020 - "PRACTICAL APPLICATION: In this study, coniferaldehyde appeared to be effective in ameliorating hepatic lipid and glucose metabolism disorders in nonalcoholic fatty liver disease by reducing the levels of intracellular triglyceride and total cholesterol and enhancing glucose uptake and intracellular glycogen content via the LKB1/AMPK signaling pathway in vitro. "
3.	Neoplasms (Cancer) 06/22/2011 - "Among them, trans-coniferylaldehyde would be a highly promising agent for cancer chemoprevention and merits further investigation." 09/08/2023 - "Network pharmacology-based analysis showed that the hit Artemisia annua constituents related to cancer targets were 3-(2-methylpropanoyl)-4-cadinene-3,11-diol, artemisinin G, O-(2-propenal) coniferaldehyde, (2-glyceryl)-O-coniferaldehyde and arteamisinin III, whereas the main cancer allied targets were NFKB1, MAP2K1 and AR. "
4.	Inflammation (Inflammations) 01/01/2021 - "Coniferyl aldehyde alleviates LPS-induced WI-38 cell apoptosis and inflammation injury via JAK2-STAT1 pathway in acute pneumonia." 09/01/2020 - "IPA showed that eugenol, muscone, and 4-hydroxy-3-methoxycinnamaldehyde were closely related to the HIF-1 and IL-15 signaling pathways, which protect against oxidative stress and inflammation, respectively. "
5.	Triploidy 07/21/2023 - "Lignin-related metabolites were differentially accumulated between triploids and diploids, among which coniferaldehyde, p-coumaryl alcohol, sinapaldehyde and coniferyl alcohol had significant positive correlations with lignin content, indicating that they might be primarily contributing metabolites. "

Related Drugs and Biologics

1.	Triglycerides (Triacylglycerol)
2.	Lipids
3.	Glycogen
4.	Glucose (Dextrose)
5.	Cholesterol
6.	Eugenol
7.	Interleukin-15 (Interleukin 15)
8.	Cytokines
9.	Lignin
10.	Guaiacol

Related Therapies and Procedures

1.	Chemoprevention
2.	Oral Administration