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tiprotimod
structure given in first source
Also Known As:
(2-(3-carboxy-1-propylthio)-4-methyl-1,3-thiazole)acetic acid; HBW 538; HBW-538; 5-Thiazoleacetic acid, 2-((3-carboxypropyl)thio)-4-methyl-
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Sulfur Compounds: 278
Thiazoles: 392
tiprotimod: 2
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Thiazoles: 392
tiprotimod: 2
Related Diseases
1.
Infections
01/01/1989 - "
We therefore examined during the course of infection the phagocytic capacity and the production of O2- -radicals (chemiluminescence) of macrophages in Tiprotimod-treated animals.
"
01/01/1989 - "
Infected animals were treated with the immunostimulator Tiprotimod after the fungal colonization of kidney was manifested (3 days post infection).
"
01/01/1989 - "
Influence of the immunostimulating substance tiprotimod on Candida albicans infection in relation to activation of macrophages.
"
10/01/1989 - "
The prophylactic treatment of NMRI mice with tiprotimod significantly prolonged the mean survival time of the animals after intravenous infection with Candida albicans 200/175 and increased the resistance to the fungal infection to 180% in comparison to controls.
"
10/01/1989 - "
In an experimental model of persistent systemic candidiasis Balb/c mice infected intravenously with Candida albicans were treated with the immunomodulator tiprotimod after the fungal colonization of kidney was manifested (3 days post infection).
"
2.
Systemic candidiasis
01/01/1989 - "
In an experimental model of persistent systemic candidiasis the effect of the thiazole compound Tiprotimod was examined.
"
10/01/1989 - "
In an experimental model of persistent systemic candidiasis Balb/c mice infected intravenously with Candida albicans were treated with the immunomodulator tiprotimod after the fungal colonization of kidney was manifested (3 days post infection).
"
3.
Neoplasms (Cancer)
10/01/1989 - "
In the syngeneic B16 melanoma tumor model tiprotimod significantly prolonged the medium survival time and reduced the number of visuable metastases in the lungs even when applied after resection of the primary tumor graft.
"
4.
Neoplasm Metastasis (Metastasis)
10/01/1989 - "
In the syngeneic B16 melanoma tumor model tiprotimod significantly prolonged the medium survival time and reduced the number of visuable metastases in the lungs even when applied after resection of the primary tumor graft.
"
5.
Mycoses (Diseases, Fungus)
10/01/1989 - "
The prophylactic treatment of NMRI mice with tiprotimod significantly prolonged the mean survival time of the animals after intravenous infection with Candida albicans 200/175 and increased the resistance to the fungal infection to 180% in comparison to controls.
"
Related Drugs and Biologics
1.
Thiazoles
2.
Immunologic Factors (Immunomodulators)
3.
Antigen-Antibody Complex (Immune Complex)