Antigen-Antibody Complex (Immune Complex)

Subscribe to Selected New Research on Antigen-Antibody Complex

8857 relevant articles (243 outcomes, 658 trials/studies) found for this Bio-Agent

Description: The complex formed by the binding of antigen and antibody molecules. The deposition of large antigen-antibody complexes leading to tissue damage causes IMMUNE COMPLEX DISEASES.

Also Known As:

Immune Complex; Antigen-Antibody Complexes; Immune Complexes; Antigen Antibody Complex; Antigen Antibody Complexes; Complex, Antigen-Antibody; Complex, Immune; Complexes, Antigen-Antibody; Complexes, Immune

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins

Proteins: 58433

Blood Proteins: 3862

Serum Globulins: 74

Immunoglobulins: 20136

Antibodies: 77322

Antigen-Antibody Complex: 8857

Immunoproteins: 30

Immunoglobulins: 20136

Antibodies: 77322

Antigen-Antibody Complex: 8857

Globulins: 305

Serum Globulins: 74

Immunoglobulins: 20136

Antibodies: 77322

Antigen-Antibody Complex: 8857

Biological Factors: 931

Antigens: 95584

Antigen-Antibody Complex: 8857

Experts

1.	Julian, Bruce A: 5 articles (01/2008 - 02/2005)
2.	Mestecky, Jiri: 5 articles (01/2008 - 02/2005)
3.	Tomana, Milan: 5 articles (01/2008 - 02/2005)
4.	Novak, Jan: 5 articles (01/2008 - 02/2005)
5.	Rönnelid, Johan: 5 articles (04/2007 - 01/2006)
6.	Haas, Mark: 5 articles (04/2007 - 09/2003)
7.	Anders, Hans-Joachim: 4 articles (08/2007 - 02/2003)
8.	Mathsson, Linda: 4 articles (04/2007 - 01/2006)
9.	van Lent, P L E M: 4 articles (03/2007 - 03/2002)
10.	van den Berg, W B: 4 articles (03/2007 - 11/2001)

Related Diseases

1.	Glomerulonephritis 10/01/2005 - "Perhaps the best treatment for glomerulonephritis is the identification and correction of any underlying inflammatory, immune-mediated or neoplastic disease that results in the deposition or formation of glomerular immune complexes. " 01/01/1996 - "Glomerular structural damage expressed as glomerular damage index was significantly greater in rats with immune complex glomerulonephritis when compared with controls (immune complex glomerulonephritis 0.91 +/- 0.13; control 0.60 +/- 0.08; P < 0.05), but was uneffected by the treatment with the CEI (immune complex) glomerulonephritis + CEI 1.02 +/- 0.26; control + CEI 0.63 +/- 0.11). " 11/22/2003 - "Assuming that a decrease in CD2AP attenuates clearance of glomerular immune complexes, patients with other types of idiopathic glomerulonephritis should also have a CD2AP mutation. " 07/01/1982 - "Impairment of glomerular clearance of macroaggregates in immune complex glomerulonephritis." 11/15/2006 - "In this study, we found that TLR4 signaling to LPS can be positively enforced by expressing gp96 on cell surfaces through the chaperone function of, but not the direct signaling by, gp96; TLR4 as well as the commensal flora are essential for the production of anti-dsDNA Ab and the immune complex-mediated glomerulonephritis in transgenic mice that express surface gp96. " Order ALL the reference details at left...
2.	Systemic Lupus Erythematosus (Libman-Sacks Disease) 12/01/2005 - "Hypocomplementaemia and low expression of CR1 on erythrocytes (E) of patients with systemic lupus erythematosus (SLE) are associated with defective clearance of circulating immune complexes (IC) and so they may have pathogenic significance. " 12/01/2000 - "Fcgamma receptor polymorphisms in systemic lupus erythematosus: association with disease and in vivo clearance of immune complexes." 01/01/2003 - "Studies of gene-targeted mice lacking specific FcgammaR have demonstrated that animals lacking activator FcgammaR on circulating leukocytes were protected from immune complex induced glomerular injury, both in models of systemic lupus erythematosus (SLE) and anti-glomerular basement membrane antibody disease. " 11/01/2002 - "OBJECTIVE: Studies of an Icelandic cohort showed that susceptibility to systemic lupus erythematosus (SLE) in individuals with C4A deficiency was increased only in the presence of increased concentrations of immune complexes. " 01/01/2001 - "A number of mouse models have been utilized to study the pathophysiology of immune complex (IC) disease, and the hallmark IC disease systemic lupus erythematosus (SLE). " Order ALL the reference details at left...
3.	Infection 07/01/1993 - "An alternative hypothesis is the possible role of defective clearance of immune complexes in the development of severe infections. " 07/01/1993 - "Pathogenesis can be related to occult infection, loss of mucosal barrier function, defective clearance of immune complexes, or aberrant immune responses. " 07/01/2004 - "These studies suggest that the presence of immune complexes in infection or autoimmunity may radically alter the nature of CD163-dependent monocyte/macrophage processes. " 11/01/1998 - "The aim of this study was to evaluate the usefulness of circulating immune complexes in the diagnosis of pneumococcal lower respiratory infection in children. " 10/01/1995 - "Our present study suggested that three mechanisms might contribute to the pathogenesis of HCV-related SjS: 1) direct infection and proliferation of HCV in salivary glands, 2) molecular mimicry between HCV and salivary glands, and 3) formation of immune complex containing HCV. " Order ALL the reference details at left...
4.	Proteinuria 01/01/2001 - "Calorie, protein, and especially fat restriction, caused a significant reduction in immune-complex deposition in the kidney, reduced proteinuria and prolongation of the mice's life span. " 11/01/1977 - "A control group of 20 immunized rats, also observed for 13 weeks, did not receive MS. MS treatment significantly decreased the incidence of heavy proteinuria (p less than 0.001), the severity of proteinuria at each week throughout the course of the disease (p less than 0.001), the amount of immune complex deposition in the glomeruli, and also delayed the onset of proteinuria (p less than 0.001). " 09/01/1995 - "The present study confirmed that the malarial-infected animals not only developed the nephritic condition (as evident by the high levels of proteinuria) but also, as indicated by the PEG assay, have the presence of high levels of circulating immune complexes in their serum. " 02/01/2008 - "We show that only a limited set of inflammatory mediators is expressed in the kidney following glomerular immune complex deposition but before the onset of proteinuria. " 11/01/2007 - "Proteinuria and renal glomerular cellularity were measured and renal immune complexes were examined by immunofluorescence. " Order ALL the reference details at left...
5.	Vasculitis (Vasculitides) 12/01/1999 - "The deposition of circulating HCV-containing immune complexes (CIC) in the skin could be the initial pathogenic event for cryoglobulinemic vasculitis; subsequently CIC could spread from the vascular bed to the perivascular tissue and then could be very rapidly eliminated. " 03/15/1992 - "In studies of immune complex (BSA-anti-BSA)-induced alveolitis and dermal vasculitis, anti-CD18 had protective effects at all doses of anti-BSA employed. " 12/01/2006 - "Biopsy is the gold standard for the diagnosis of cutaneous vasculitis and also necessary for the detection of cutaneous vascular immune complexes by direct immunofluorescence. " 08/01/1989 - "Even vasculitis may be a consequence of failure of clearance of immune complexes from the interstitium. " 02/01/1997 - "Immunofluorescence study suggested the occurrence of an immune complex nephropathy and a pauci-immune pathogenesis of vasculitis. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Immunoglobulin G (IgG)
2.	Antibodies
3.	Complement System Proteins (Complement)
4.	Immunoglobulin A (IgA)
5.	Antigens
6.	Antigen-Antibody Complex (Immune Complex)
7.	Autoantibodies
8.	Immunoglobulins (Immunoglobulin)
9.	Immunoglobulin M (IgM)
10.	Rheumatoid Factor

Related Therapies and Procedures

1.	Plasmapheresis
2.	Drug Therapy (Chemotherapy)
3.	Plasma Exchange
4.	Splenectomy
5.	Injections

Best Treatments:
Research Summary Report
on Glomerulonephritis

CureHunter Patient-Physician Summary Reports collect in one document all the medications ever reported in the US National Library of Medicine—1949 to the present—to be effective against your target disease. CureHunter research summary reports will vary in length from 25 to 250 pages. Analytic charts allow you and your physicians to see at a glance your medication options—including new, promising, off-label and experimental all rated for clinical efficacy.

Free Updates for 1 Year
All 320 Outcomes
Top 200 Key Drugs and Biologics
Top 50 Key Therapies and Procedures
Detailed History Charts
Full Research Reference Details
Sample PDF Report on Psoriasis >>

Price:

$24.00 & Delivery via PDF download
updates for 1 year

Research Interface

Rapidly retrieve summaries of all the evidence for any disease in seconds. Save hours of search and analysis time. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time.

Unlimited Disease, Drug and Therapy Search
2 clicks from Disease to Drug to Evidence
Trial References
All the Positive Outcomes
Detailed Relationship Timeline Charts
Full Article Reference Details
Includes Mobile Interface Subscription
One-click to FDA Products/Patents
Request Institution License Details >>

Price:

$490.00 access via web interface
1 year subscription

Proceed to Checkout >>

Mobile Interface

Retrieve summaries of all the evidence for any disease from your Mobile Phone or PDA. Accelerate decision making in the field. Speed up your study of new drug and disease domains. Refresh your knowledge on the road.

Access from any web enabled PDA or Phone
Trial references
All the Positive Outcomes
Drug and Therapy searches
Full Article Reference Details
Try Mobile Interface >>

Price:

$45.00 access via "curehunter.com/m"
1 year subscription

Proceed to Checkout >>