|1.||Nafziger, Joëlle: 1 article (10/2005)|
|2.||Bernard, Natacha: 1 article (10/2005)|
|3.||Guillosson, Jean-Jacques: 1 article (10/2005)|
|4.||Arock, Michel: 1 article (10/2005)|
|5.||Devevey, Lionel: 1 article (10/2005)|
|6.||Jacquemont, Céline: 1 article (10/2005)|
|7.||Helissey, Philippe: 1 article (10/2005)|
|8.||Chrétien, Pascale: 1 article (10/2005)|
|9.||Nishida, Keiko: 1 article (11/2004)|
|10.||Taguchi, Osamu: 1 article (11/2004)|
10/01/2005 - "Leukemia was chemically induced in male WKAH/Hkm rats by a nitrosourea derivative, N-butylnitrosourea (BNU), an alkylating agent, administered orally 5 days a week for 24 weeks. "
03/01/1992 - "The initial histological changes of leukemia were investigated in rats to which 1-ethyl-1-nitrosourea and 1-butyl-1-nitrosourea were orally administered. "
03/01/1992 - "Initial changes of rat leukemia induced by 1-ethyl-1-nitrosourea and 1-butyl-1-nitrosourea."
10/15/1982 - "Chromosome changes in butylnitrosourea (BNU)-induced mouse leukemia."
02/01/1977 - "Hematological characteristics of N-nitrosobutylurea-induced W/Fu rat leukemia L1504 and L1005."
02/01/1977 - "Localization and histological findings of the nervous tumors were similar to those observed previously in rats whose mothers received 1-butyl-1-nitrosourea (BNU) during pregnancy. "
06/01/1975 - "Considerable number (8.2 approximately 10.7%) of ovarian tumors were produced in Sprague-Dawley adult rats treated with multiple oral or intramuscular administration of heavy doses of N-butylnitrosourea. "
06/01/1975 - "Induction of ovarian tumor in rats with N-butylnitrosourea."
01/01/1984 - "Induction of digestive-tract tumors in F344 rats by continuous oral administration of N-butyl-N-nitrosourea."
04/01/1983 - "Tumor induction by a single subcutaneous injection of 1-butyl-1-nitrosourea or 1-butylurea in newborn mice."
01/01/1984 - "Butylnitrosourea (BNU) was used to induce thymic lymphomas in BDF1 mice. "
01/01/1983 - "BDF1 mice were exposed to butylnitrosourea for 12 weeks (BNU, 0.02% in the drinking water) and died of thymic lymphomas with median latency periods of 12-20 weeks. "
11/01/2004 - "When N-butyl-N-nitrosourea (NBU), a chemical carcinogen, was administered orally to B6 and C3H strains, lymphoma development was slower than in T3(b)-TL gene-transduced counterpart strains expressing TL ubiquitously as self-antigens, suggesting that anti-TL immunity may play a protective role. "
11/01/2004 - "Immunity against mouse thymus-leukemia antigen (TL) protects against development of lymphomas induced by a chemical carcinogen, N-butyl-N-nitrosourea."
04/01/1983 - "A subcutaneous injection of 1-butyl-1-nitrosourea (BNU) at the maximum tolerated dose (333 mg/kg body wt.) to newborn CDF1 mice induced adenocarcinoma and adenoma of the lung, adenoma of the liver, thymic or non-thymic lymphoma and neurinoma of the acusticus nerve; the total incidence of tumors was statistically significant as compared with that of control. "
|4.||Chromosome Aberrations (Chromosome Abnormalities)
01/01/1994 - "The frequency of chromosome aberrations (CA) induced by n-butyl-N-nitrosourea or methylmethanesulfonate (MMS), which does not need metabolic activation, was significantly higher in both LEA and LEC rats than in Wistar or SD rats. "
10/01/1981 - "The chromosomal distribution of chromosome aberrations (CA) and sister chromatid exchanges (SCE) induced by various chemical carcinogens such as 7,12-dimethylbenz[a]anthracene, 7,8,12-trimethylbenz[a]anthracene, 1-butyl-1-nitrosourea, urethan, 4-nitroquinoline 1-oxide, 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide, and the antineoplastic compound mitomycin C was studied with the use of noninbred Long-Evans male rat bone marrow cells in vivo and in vitro. "
10/01/1985 - "The effects of the carcinogens (4NQO, 4-nitroquinoline-N-oxide; MNNG, N-methyl-N'-nitro-N-nitrosoguanidine; AFLG1, aflatoxin G1; AFLB1, aflatoxin B1; BNU, butylnitrosourea; MNU, methylnitrosourea) and the tumor promoter (TPA, 12-O-tetradecanoylphorbol-13-acetate) on sister chromatid exchanges (SCE), chromosome aberrations and colony formation (CF) were examined in three types of Bloom syndrome (BS) B-lymphoblastoid cell lines (B-LCLs); type I with normal SCE and normal karyotype; type II with high SCE and normal karyotypes; type III with high SCE and abnormal karyotypes. "
|5.||T-Cell Leukemia (Leukemia, T Cell)
10/01/1983 - "T-cell leukemias have been induced in adult BDF1 mice by 12 or 15 weeks of exposure to butylnitrosourea (BNU) in the drinking water. "
01/01/1983 - "A butylnitrosourea-induced murine T-cell leukemia, L40, was transplanted in BDF1 mice; 1 X 10(3) cells killed all recipients after conditioning with 400 rad, whereas 1 X 10(5) were needed with normal recipients. "
|7.||Aflatoxin B1 (Aflatoxin B)
|9.||4-Nitroquinoline-1-oxide (4 Nitroquinoline 1 oxide)
|10.||Urethane (Ethyl Carbamate)
|3.||Drug Therapy (Chemotherapy)