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Successful treatment of Grover's disease with calcipotriol.

Abstract
We report the case of an 84-year-old man with clinical, histological and electron-microscopic features of a Darier-like pattern of Grover's disease. The lesions had a persistent course, with a 5-month history before diagnosis and a clinical onset 2 years after the surgical removal of a cholangiocarcinoma. A significant clinical improvement was observed after a three-week course of calcipotriol ointment applied as a monotherapy regimen. Clinical uses of topical calcipotriol in dermatological conditions are reviewed with emphasis on dyskeratotic disorders.
AuthorsA V Mota, T M Correia, J M Lopes, J M Guimarães
JournalEuropean journal of dermatology : EJD (Eur J Dermatol) 1998 Jan-Feb Vol. 8 Issue 1 Pg. 33-5 ISSN: 1167-1122 [Print] France
PMID9649669 (Publication Type: Case Reports, Journal Article, Review)
Chemical References
  • Dermatologic Agents
  • calcipotriene
  • Calcitriol
Topics
  • Acantholysis (drug therapy, pathology)
  • Administration, Topical
  • Aged
  • Aged, 80 and over
  • Calcitriol (analogs & derivatives, therapeutic use)
  • Dermatologic Agents (therapeutic use)
  • Follow-Up Studies
  • Humans
  • Male
  • Treatment Outcome

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