Economic, clinical and functional consequences of a treatment using metrenperone during an outbreak of shipping fever in cattle.

Abstract

Eighteen of 91 seven- to nine-month-old Belgian white and blue double-muscled male fattening cattle developed typical signs of shipping fever. They were all injected intramuscularly once a day for three days with 5 mg/kg of enrofloxacin, and in addition nine selected at random were injected intramuscularly five times at 12 hour intervals with 0.1 mg/kg of metrenperone, a 5-hydroxytryptamine blocker, the other nine receiving a placebo. During the outbreak of shipping fever metrenperone showed effective antipyretic properties, and all the calves treated with it made a complete recovery. Moreover, during the 360 day fattening period following the outbreak, the cattle treated with metrenperone gained on average 45.4 kg more weight than the control cattle.

• Authors: B Genicot, F Mouligneau, F Rollin, J K Lindsey, R Close, P Lekeux
• Journal: The Veterinary record (Vet Rec) Vol. 132 Issue 10 Pg. 245-7 (Mar 06 1993) ISSN: 0042-4900 [Print] England
• PMID: 8384736 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Infective Agents
• Fluoroquinolones
• Piperidines
• Quinolones
• Enrofloxacin
• metrenperone

Topics

• Animals
• Anti-Infective Agents
• Cattle
• Disease Outbreaks (veterinary)
• Drug Therapy, Combination
• Enrofloxacin
• Fluoroquinolones
• Injections, Intramuscular (veterinary)
• Male
• Pasteurellosis, Pneumonic (drug therapy, epidemiology, physiopathology)
• Piperidines (administration & dosage, pharmacology, therapeutic use)
• Quinolones (administration & dosage, pharmacology, therapeutic use)
• Respiration
• Respiratory Function Tests (veterinary)
• Weight Gain