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Adult pancreatic nesidioblastosis. Unusual presentations of a rare entity.

Abstract
Adult nesidioblastosis remains an uncommon and poorly understood condition creating both diagnostic and therapeutic dilemmas for clinicians. Despite the totipotent nature of hyperplastic pancreatic cells, nearly all accounts of nesidioblastosis described patients with symptoms of hypoglycemia. We herein describe two unique patients with adult nesidioblastosis with gastrin and pancreatic polypeptide secretion. Surgical resection rendered these two patients free of disease.
AuthorsD R Farley, J A van Heerden, J L Myers
JournalArchives of surgery (Chicago, Ill. : 1960) (Arch Surg) Vol. 129 Issue 3 Pg. 329-32 (Mar 1994) ISSN: 0004-0010 [Print] United States
PMID8129611 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Gastrins
  • Pancreatic Polypeptide
Topics
  • Aged
  • Duodenum (surgery)
  • Gastrins (metabolism)
  • Humans
  • Male
  • Middle Aged
  • Pancreatectomy
  • Pancreatic Diseases (pathology, physiopathology, surgery)
  • Pancreatic Polypeptide (metabolism)

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