[Effective treatment of recurrent keratoacanthoma using methotrexate].

Abstract

Three patients, two men aged 54 and 72 years, respectively, and a woman aged 52 years, were treated successfully for (recurrence of a) keratoacanthoma with methotrexate. Since the sixties 11 patients with recurrent keratoacanthoma treated with methotrexate have been described. Dose schedules were widely different and dosages were in general high, resulting in more or less severe side effects. The patients now presented were treated according to the Weinstein schedule, with small doses and during a short period, which minimises the adverse effects.

• Authors: G H Schoon-Blaauw, P J Berretty, A H Ideler, I Tan-Go
• Journal: Nederlands tijdschrift voor geneeskunde (Ned Tijdschr Geneeskd) Vol. 138 Issue 8 Pg. 410-3 (Feb 19 1994) ISSN: 0028-2162 [Print] Netherlands
• Vernacular Title: Effectieve behandeling van recidiverend kerato-acanthoom met methotrexaat.
• PMID: 8127383 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Methotrexate

Topics

• Aged
• Drug Administration Schedule
• Ear, External
• Female
• Forehead
• Humans
• Keratoacanthoma (drug therapy)
• Male
• Methotrexate (administration & dosage, therapeutic use)
• Middle Aged
• Nose
• Recurrence
• Skin Diseases (drug therapy)