[Lipid and phospholipid composition of blood plasma and erythrocyte membranes in children with hemorrhagic vasculitis].

Abstract

Thin-layer chromatography examination of serum and red cell membrane lipids and phospholipids has been conducted in 37 children with hemorrhagic vasculitis. The authors found: hyperlipidemia resultant from high concentrations of triglycerides, changes in phospholipid fractions due to a relative rise in the level of phosphatidylethanolamine, altered spectrum of red cell membrane lipids due to a significant increase in free cholesterol against low triglycerides. The above shifts may cause hypercoagulation and microcirculatory affections. The conclusion is made on the necessity of correcting impaired lipid spectrum of blood plasma and red cell membrane when conducting basic therapy of hemorrhagic vasculitis.

• Authors: A V Mazurin, T G Plakhuta, V N Spiridonova, I N Tsymbal, S S Galaeva
• Journal: Gematologiia i transfuziologiia (Gematol Transfuziol) 1994 Mar-Apr Vol. 39 Issue 2 Pg. 37-9 ISSN: 0234-5730 [Print] Russia (Federation)
• Vernacular Title: Osobennosti lipidnogo i fosfolipidnogo sostava plazmy krovi i membran éritrotsitov pri gemorragicheskom vaskulite u deteĭ.
• PMID: 8026688 (Publication Type: Journal Article)

Chemical References

• Lipids
• Phospholipids

Topics

• Adolescent
• Child
• Child, Preschool
• Erythrocyte Membrane (metabolism)
• Female
• Humans
• IgA Vasculitis (blood)
• Lipids (blood)
• Male
• Phospholipids (blood)