Bilateral acetylsulfapyridine nephrolithiasis associated with chronic sulfasalazine therapy.

Abstract	We report on formation of bilateral renal calculi secondary to sulfasalazine therapy for juvenile rheumatoid arthritis. The condition was successfully treated with extracorporeal shock wave lithotripsy. Analysis of the fragments with thin layer chromatography and nuclear magnetic resonance revealed acetylsulfapyridine, a metabolite of sulfasalazine.
Authors	E Erturk, J B Casemento, K R Guertin, A S Kende
Journal	The Journal of urology (J Urol) Vol. 151 Issue 6 Pg. 1605-6 (Jun 1994) ISSN: 0022-5347 [Print] United States
PMID	7910643 (Publication Type: Case Reports, Journal Article)
Chemical References	N-acetylsulfapyridine Sulfasalazine Sulfapyridine
Topics	Adult Female Humans Kidney Calculi (chemically induced, chemistry, metabolism) Sulfapyridine (analogs & derivatives, analysis, metabolism) Sulfasalazine (adverse effects, metabolism)

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