Disseminated Nocardia transvalensis infection resembling pulmonary infarction in a liver transplant recipient.

Abstract

Infections due to Nocardia transvalensis are extremely rare: only four disseminated infections with this pathogen have been reported, three of which ended fatally. This is the first report of a liver transplant recipient with Nocardia transvalensis infection. The patient had disseminated infection with pulmonary involvement, which presented as pulmonary infarction. Despite a ten-day delay in the administration of correct therapy, he responded rapidly to trimethoprim-sulfamethoxazole. The pitfalls of differentiating nocardial infection from pulmonary thromboembolism in solid organ transplant recipients and the diagnostic considerations unique to liver transplant recipients are discussed.

• Authors: M Weinberger, A Eid, L Schreiber, M Shapiro, Y Ilan, E Libson, T Sacks, R Tur-Kaspa
• Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology (Eur J Clin Microbiol Infect Dis) Vol. 14 Issue 4 Pg. 337-41 (Apr 1995) ISSN: 0934-9723 [Print] Germany
• PMID: 7649197 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Trimethoprim, Sulfamethoxazole Drug Combination

Topics

• Bacteremia (diagnosis, drug therapy, immunology)
• Diagnosis, Differential
• Humans
• Immunocompromised Host
• Liver Transplantation (immunology)
• Male
• Middle Aged
• Nocardia Infections (diagnosis, drug therapy, immunology)
• Pulmonary Embolism (diagnosis)
• Trimethoprim, Sulfamethoxazole Drug Combination (administration & dosage, therapeutic use)