[Spontaneous oral dyskinesia. Successful treatment with tetrabenazine (author's transl)].

Abstract

Tetrabenazine (50-150 mg/day) was a moderate to excellent efficacy in each of six patients with severe spontaneous oral dyskinesia. Slight akinesia, rigidity, and transient disorientation were occasional side effects that could easily be controlled and were tolerated by the patient in view of the lasting amelioration of this debilitating symptom. When tetrabenazine was administered for blepharospasm, only two of six cases showed partial improvement with more severe side effects.

• Authors: F Schumm, J Dichgans, E Zeller
• Journal: Archiv fur Psychiatrie und Nervenkrankheiten (Arch Psychiatr Nervenkr (1970)) Vol. 230 Issue 4 Pg. 315-23 ( 1981) Germany
• Vernacular Title: Spontane orale Dyskinesien. Erfolgreiche Therapie mit Tetrabenazin (Nitoman).
• PMID: 7316728 (Publication Type: English Abstract, Journal Article)

Chemical References

• Receptors, Dopamine
• Tetrabenazine

Topics

• Aged
• Basal Ganglia Diseases (drug therapy)
• Blepharospasm (drug therapy)
• Dose-Response Relationship, Drug
• Female
• Humans
• Male
• Masticatory Muscles (drug effects)
• Movement Disorders (drug therapy)
• Receptors, Dopamine (drug effects)
• Tetrabenazine (therapeutic use)