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O6-methylguanine, but not N7-methylguanine or N3-methyladenine, induces gene mutations, sister-chromatid exchanges and chromosomal aberrations in Chinese hamster cells.

AuthorsB Kaina, K Heindorff, O Aurich
JournalMutation research (Mutat Res) Vol. 108 Issue 1-3 Pg. 279-92 (Mar 1983) ISSN: 0027-5107 [Print] Netherlands
PMID6835224 (Publication Type: Journal Article)
Chemical References
  • 3-methyladenine
  • Guanine
  • 7-methylguanine
  • O-(6)-methylguanine
  • Adenine
Topics
  • Adenine (analogs & derivatives, pharmacology)
  • Animals
  • Cells, Cultured
  • Chromosome Aberrations
  • Cricetinae
  • Crossing Over, Genetic (drug effects)
  • Dose-Response Relationship, Drug
  • Guanine (analogs & derivatives, pharmacology)
  • Karyotyping
  • Mutation (drug effects)
  • Sister Chromatid Exchange (drug effects)

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