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The absolute configuration of urinary 2-hydroxybutyric acid in patients with ketosis and lactic acidosis.

Abstract
The absolute configurations of urinary 2-hydroxybutyrate and 3-hydroxybutyrate were determined in patients with lactic acidemia and ketosis by capillary gas-liquid chromatography of their O-acetylated (--)-menthyl ester derivatives. 2-Hydroxybutyrate had the L-configuration, whereas 3-hydroxybutyrate was in the D-configuration.
AuthorsJ P Kamerling, G J Gerwig, M Duran, D Ketting, S K Wadman
JournalClinica chimica acta; international journal of clinical chemistry (Clin Chim Acta) Vol. 88 Issue 1 Pg. 183-8 (Aug 15 1978) ISSN: 0009-8981 [Print] Netherlands
PMID679487 (Publication Type: Journal Article)
Chemical References
  • Hydroxybutyrates
  • Lactates
Topics
  • Acidosis (urine)
  • Chromatography, Gas (methods)
  • Humans
  • Hydroxybutyrates (urine)
  • Isomerism
  • Ketosis (urine)
  • Lactates (blood, urine)
  • Mass Spectrometry
  • Molecular Conformation
  • Stereoisomerism

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