[Clinical experience of Hachimijiogan for male infertility patients].

Abstract

We treated 53 patients for male infertility with TSUMURA - Hachimijiogan given as a daily dose of 7.5 g for 144 days on the average. The sperm density was improved by administration to 10 X 10(6)/ml or more in 22 patients (41.5%) and lowered to 10 X 10(6)/ml or more in only 2 patients (3.8%). The sperm motility was improved by 10% or over in 29 patients (54.7%) as compared with 5 patients (9.4%) in whom it was lowered by 10% or more. The sperm motile efficiency index ( SMEI ) was improved in 40 (75.5%) of the 53 patients. Statistically significant differences were noted in the improvement in sperm density, sperm motility and SMEI . By contrast, there was no difference in semen volume, sperm morphology or sperm agglutination between the pre- and post- treatment periods. During the period of treatment, the wives of 4 patients (7.5%) conceived children. These results suggest that TSUMURA - Hachimijiogan is effective for male infertility to a certain extent and that clinical trials on its use for male infertility may be meaningful.

• Authors: K Miura, M Matsuhashi, A Maki, M Takanami, K Fujio, K Nakayama, M Shirai, K Ando
• Journal: Hinyokika kiyo. Acta urologica Japonica (Hinyokika Kiyo) Vol. 30 Issue 1 Pg. 97-102 (Jan 1984) ISSN: 0018-1994 [Print] Japan
• PMID: 6731200 (Publication Type: English Abstract, Journal Article)

Chemical References

• Plant Extracts

Topics

• Adult
• Drug Evaluation
• Female
• Humans
• Infertility, Male (drug therapy, physiopathology)
• Male
• Plant Extracts (therapeutic use)
• Plants, Medicinal
• Pregnancy
• Sperm Count
• Sperm Motility (drug effects)
• Spermatozoa (drug effects)