Comparative efficacy of piperacillin and penicillin G in treatment of gonococcal urethritis.

Abstract

The comparative efficacy of 2 g of piperacillin and 4.8 X 10(6) U of penicillin G in the treatment of uncomplicated gonococcal urethritis was assessed in a randomized prospective study. Sixty-five evaluable patients received piperacillin, and 55 received penicillin G. All patients received either therapy were cured of gonorrhea. We conclude that piperacillin is as efficacious as aqueous procaine penicillin G in the therapy of uncomplicated gonococcal urethritis.

• Authors: S J Landis, R Ramphal, B J Mansheim, K H Rand, J W Shands Jr
• Journal: Antimicrobial agents and chemotherapy (Antimicrob Agents Chemother) Vol. 20 Issue 5 Pg. 693-5 (Nov 1981) ISSN: 0066-4804 [Print] United States
• PMID: 6459764 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Penicillins
• Penicillin G Procaine
• Piperacillin

Topics

• Gonorrhea (complications)
• Humans
• Male
• Microbial Sensitivity Tests
• Penicillin G Procaine (therapeutic use)
• Penicillins (therapeutic use)
• Piperacillin
• Urethritis (drug therapy, etiology)