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The role of caudate nucleus in dermorphin-induced catalepsy in rats.

Abstract
Bilateral electrolytic lesions of caudate nucleus were observed to potentiate the cataleptic response, and to prevent the muscular rigidity produced by intracerebroventricular injection or infusion of dermorphin. These results suggest that caudate nucleus plays an inhibitory role in controlling the cataleptic response and its integrity is essential for full development of dermorphin-induced rigidity.
AuthorsG Improta, A Guglietta
JournalPeptides (Peptides) Vol. 6 Suppl 3 Pg. 161-4 ( 1985) ISSN: 0196-9781 [Print] United States
PMID3831960 (Publication Type: Journal Article)
Chemical References
  • Oligopeptides
  • Opioid Peptides
  • dermorphin
Topics
  • Animals
  • Catalepsy (chemically induced)
  • Caudate Nucleus (drug effects, physiology)
  • Corpus Striatum (physiology)
  • Injections, Intraventricular
  • Male
  • Muscle Rigidity (chemically induced)
  • Oligopeptides (pharmacology)
  • Opioid Peptides
  • Pain (physiopathology)
  • Rats

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