Abstract | INTRODUCTION: METHODS: Relevant articles were retrieved through PubMed, Web of Science, EMBASE, Cochrane Library, China National Knowledge Infrastructure (CNKI) and other databases. Serum 25-hydroxyvitamin D [25( OH) D] levels and vitamin D deficiency were used as our primary outcome. The odds ratio (OR) and the standardized mean difference (SMD) with 95% confidence interval were both examined for vitamin D deficiency and levels. RESULTS: Our meta-analysis had included a total of 3374 non- scarring alopecia patients and 7296 healthy controls from 23 studies through the inclusion criteria and exclusion criteria. We found non- scarring alopecia had decreased serum 25( OH)D level (WMD -7.29; 95% CI -9.21, -5.38) and increased vitamin D deficiency incidence (OR 3.11 95% CI 2.29, 4.22), compared with healthy controls. This meta-analysis chose to conduct random-effect model and subgroup analysis, because of the high heterogeneity (serum 25( OH)D level: I2 = 95%, vitamin D deficiency: I2 = 0%). CONCLUSION:
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Authors | Yuling Chen, Xin Dong, Yixin Wang, Yu Li, Lidan Xiong, Li Li |
Journal | Journal of cosmetic dermatology
(J Cosmet Dermatol)
(Nov 27 2023)
ISSN: 1473-2165 [Electronic] England |
PMID | 38010941
(Publication Type: Journal Article, Review)
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Copyright | © 2023 The Authors. Journal of Cosmetic Dermatology published by Wiley Periodicals LLC. |