Abstract |
Cryptococcal immune reconstitution inflammatory syndrome (C-IRIS) is a condition that affects immunosuppressed individuals recruited to antiretroviral therapy. In a recent publication, Kawano and colleagues used a mouse model to demonstrate that pulmonary dysfunction, one of the fatal complications of C-IRIS, is caused by T cell-driven neurodegeneration in a vital medullary nucleus of the brain responsible for respiratory control.
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Authors | Rachael Dangarembizi, Rebecca Drummond |
Journal | Trends in neurosciences
(Trends Neurosci)
Vol. 46
Issue 12
Pg. 1003-1004
(Dec 2023)
ISSN: 1878-108X [Electronic] England |
PMID | 37806831
(Publication Type: Journal Article)
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Copyright | Copyright © 2023 Elsevier Ltd. All rights reserved. |
Chemical References |
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Topics |
- Animals
- Mice
- AIDS-Related Opportunistic Infections
(complications, drug therapy)
- Meningitis, Cryptococcal
(complications, drug therapy)
- Antifungal Agents
(therapeutic use)
- HIV Infections
(complications, drug therapy)
- Mesencephalon
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