Carteolol treatment of essential hypertension: a long-term study of safety and efficacy.

Abstract

The long-term safety and antihypertensive efficacy of carteolol were evaluated in an open-label, multicenter trial of 245 hypertensive patients. For those patients maintained on carteolol monotherapy, three months of treatment with once-daily oral doses of carteolol ranging from 2.5 to 60 mg reduced the mean recumbent blood pressure by 12/14 mm Hg from baseline values of 151/100. Blood pressure reductions observed at three months were maintained throughout the study. The final daily dose of carteolol for most patients was 10 mg or less. Carteolol was shown to be safe and well tolerated by most patients.

• Authors: R R Luther, C J Maurath, M J Klepper, R O Peckinpaugh, G L Ringham
• Journal: The Journal of international medical research (J Int Med Res) Vol. 14 Issue 4 Pg. 175-84 ( 1986) ISSN: 0300-0605 [Print] England
• PMID: 3758467 (Publication Type: Journal Article)

Chemical References

• Propanolamines
• Carteolol

Topics

• Adult
• Aged
• Body Weight
• Carteolol (administration & dosage, adverse effects, therapeutic use)
• Electrocardiography
• Female
• Humans
• Hypertension (blood, diagnostic imaging, drug therapy)
• Male
• Middle Aged
• Propanolamines (therapeutic use)
• Pulse (drug effects)
• Radiography
• Time Factors