Abstract | BACKGROUND: METHODS: Studies comparing the clinical efficacy of structural and nonstructural bone grafting via the posterior approach in spinal tuberculosis surgery were identified from 8 databases from inception to August 2022. Study selection, data extraction, and evaluation of the risk of bias were performed, and meta-analysis was conducted. RESULTS: Ten studies including 528 patients with spinal tuberculosis were enrolled. Meta-analysis revealed no between-group differences in fusion rate (P = 0.29), complications (P = 0.21), postoperative Cobb angle (P = 0.7), visual analog scale score (P = 0.66), erythrocyte sedimentation rate (P = 0.74), or C-reactive protein level (P = 0.14) at the final follow-up. Nonstructural bone grafting was associated with less intraoperative blood loss (P < 0.00001), shorter operation time (P < 0.0001), shorter fusion time (P < 0.01), and shorter hospital stay (P < 0.00001), while structural bone grafting was associated with lower Cobb angle loss (P = 0.002). CONCLUSIONS:
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Authors | Yanchun Zhong, Yuxi Huang, Zhaoyuan Chen, Zhenxing Liu, Wuyang Liu, Jiaquan Luo, Yongjun Ye |
Journal | World neurosurgery
(World Neurosurg)
Vol. 174
Pg. 42-51
(Jun 2023)
ISSN: 1878-8769 [Electronic] United States |
PMID | 36906088
(Publication Type: Meta-Analysis, Systematic Review, Journal Article, Review)
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Copyright | Copyright © 2023 Elsevier Inc. All rights reserved. |
Topics |
- Humans
- Tuberculosis, Spinal
(diagnostic imaging, surgery)
- Retrospective Studies
- Bone Transplantation
(methods)
- Spinal Fusion
(methods)
- Thoracic Vertebrae
(surgery)
- Treatment Outcome
- Debridement
- Lumbar Vertebrae
(surgery)
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