Multicentric reticulohistiocytosis with eosinophilic gastroenteritis: An unusual relationship.

Abstract

Multicentric reticulohistiocytosis (MRH) is a rare disease with poorly defined therapeutic strategies. Here, we report the case of a patient with eosinophilic gastroenteritis who developed MRH after 5 years. The patient presented with disabling and rapidly progressive polyarthralgia, eosinophilic gastroenteritis, and resistance to first-line therapies. However, there was a marked improvement in the arthritis symptoms following treatment with tofacitinib. This presentation provides a useful perspective for the therapeutic management of complex scenarios involving MRH.

• Authors: Junyu Fan, Ting Jiang, Yingying Qin, Qin Ding, Xia Cheng, Dongyi He
• Journal: International journal of rheumatic diseases (Int J Rheum Dis) Vol. 26 Issue 7 Pg. 1377-1380 (Jul 2023) ISSN: 1756-185X [Electronic] England
• PMID: 36823772 (Publication Type: Case Reports)
• Copyright: © 2023 Asia Pacific League of Associations for Rheumatology and John Wiley & Sons Australia, Ltd.

Topics

• Humans
• Histiocytosis, Non-Langerhans-Cell (diagnosis, drug therapy)
• Enteritis
• Eosinophilia (complications, diagnosis, drug therapy)
• Arthritis (diagnosis)