Assessing the role of minimally invasive radical hysterectomy for early-stage cervical cancer.

Abstract

Surgery is the mainstay of treatment in the management of early-stage cervical cancer. Until the publication of the Laparoscopic Approach to Cervical Cancer (LACC) trial, minimally invasive radical hysterectomy was the recommended approach to treat patients with early-stage disease. The results of the LACC trial questioned the adoption of minimally invasive surgery in cervical cancer. In comparison with the open approach, minimally invasive surgery correlated with worse disease-free and cancer-specific survival. Similarly, other retrospective studies highlighted this correlation, thus corroborating the results of the LACC trials. In the present review, we evaluated current evidence and further prospective of the adoption of minimally invasive radical hysterectomy in cervical cancer. Moreover, we sought to assess some unsolved issues regarding the role of minimally invasive surgery in early-stage cervical cancer patients.

• Authors: Giorgio Bogani, Violante Di Donato, Ludovico Muzii, Jvan Casarin, Fabio Ghezzi, Mario Malzoni, Stefano Greggi, Fabio Landoni, Luca Bazzurini, Vanna Zanagnolo, Francesco Multinu, Roberto Angioli, Francesco Plotti, Giuseppe Caruso, Margherita Fischetti, Gabriella Ferrandina, Innocenza Palaia, Pierluigi Benedetti Panici, Giovanni Scambia, Francesco Raspagliesi
• Journal: European journal of obstetrics, gynecology, and reproductive biology (Eur J Obstet Gynecol Reprod Biol) Vol. 275 Pg. 64-69 (Aug 2022) ISSN: 1872-7654 [Electronic] Ireland
• PMID: 35753229 (Publication Type: Journal Article, Review)
• Copyright: Copyright © 2022. Published by Elsevier B.V.

Topics

• Female
• Humans
• Hysterectomy (methods)
• Laparoscopy (methods)
• Minimally Invasive Surgical Procedures (methods)
• Neoplasm Staging
• Retrospective Studies
• Uterine Cervical Neoplasms (pathology)