Abstract | BACKGROUND: There is increasing concern regarding efficacy of organ preservation protocol in laryngeal and hypopharyngeal cancers. METHOD: RESULTS: Seventy-six patients (39.8 per cent) had a primary cancer in the larynx, and 115 patients (60.2 per cent) had a primary cancer in the hypopharynx. The median follow up was 39 months. The 3-year time to progression, overall survival, local control and laryngectomy free survival was 56.2 per cent, 76.3 per cent, 73.2 per cent and 67.2 per cent, respectively. At the time of analysis, 83 patients (43.5 per cent) were alive and disease free at their last follow up and did not require tube feeding or tracheostomy. The laryngo-oesophageal dysfunction-free survival was 61 per cent at 3 years. CONCLUSION: Organ conservation protocols remain the standard of treatment in appropriately selected patients with laryngeal and hypopharyngeal cancers.
|
Authors | S Sood, S Sinha, A Balaji, S R Mundhe, N Mummudi, A Budrukkar, M Swain, K Prabash, V Noronha, A Joshi, V Patil, S G Laskar |
Journal | The Journal of laryngology and otology
(J Laryngol Otol)
Vol. 137
Issue 4
Pg. 448-454
(Apr 2023)
ISSN: 1748-5460 [Electronic] England |
PMID | 35678378
(Publication Type: Journal Article)
|
Topics |
- Humans
- Hypopharyngeal Neoplasms
(surgery, pathology)
- Retrospective Studies
- Organ Preservation
- Laryngeal Neoplasms
(surgery, pathology)
- Larynx
(surgery, pathology)
|