Abstract | INTRODUCTION: PRESENTATION OF CASE: Herein, we report the case of a 56-year-old patient diagnosed with stage IVB endometrial cancer. After eight cycles of first-line chemotherapy, computed tomography (CT) revealed relapse with re-enlargement of the para-aortic lymph nodes. Since the primary tumour had high microsatellite instability, we switched to pembrolizumab treatment. Pembrolizumab was effective but could not be continued due to adverse events after 10 cycles. Positron emission tomography-CT revealed active cancer in the uterus and para-aortic lymph nodes. DISCUSSION: Since pembrolizumab treatment had to be discontinued, we performed salvage surgery, which achieved complete tumour removal, and the patient has had no evidence of disease for 16 months. CONCLUSION:
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Authors | Tomomi Taguchi, Kimihiko Ito, Michiko Yamashita, Tomomi Egawa-Takata |
Journal | International journal of surgery case reports
(Int J Surg Case Rep)
Vol. 94
Pg. 107125
(May 2022)
ISSN: 2210-2612 [Print] Netherlands |
PMID | 35658296
(Publication Type: Journal Article)
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Copyright | Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved. |