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Modulation of cancer immunotherapy by dietary fibers and over-the-counter probiotics.

Abstract
The human gut microbiota has a major impact on cancer immunosurveillance. In a recent Science paper, Spencer et al. reported the interesting observation that low dietary fiber intake or ingestion of commercially available probiotics both affect the anticancer effects mediated by immunotherapy in mice and patients with advanced melanoma.
AuthorsLaurence Zitvogel, Lisa Derosa, Guido Kroemer
JournalCell metabolism (Cell Metab) Vol. 34 Issue 3 Pg. 350-352 (03 01 2022) ISSN: 1932-7420 [Electronic] United States
PMID35235771 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Comment)
CopyrightCopyright © 2022 Elsevier Inc. All rights reserved.
Chemical References
  • Dietary Fiber
Topics
  • Animals
  • Dietary Fiber (therapeutic use)
  • Gastrointestinal Microbiome (physiology)
  • Humans
  • Immunotherapy
  • Melanoma
  • Mice
  • Probiotics (pharmacology, therapeutic use)

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