Clinical and Molecular Characteristics of Rare Malignant Tumors of Colon and Rectum.

Abstract

The most frequent form of colorectal cancer is represented by adenocarcinoma being about 98% of tumor histological types. However, other rare histotypes can be found in colon and rectum (adenosquamous, goblet cell adenocarcinoma, lymphoma, medullary carcinoma, melanoma, mesenchymal, neuroendocrine, plasmacytoma, signet ring, squamous tumors). Altogether, these forms account for less than 2% of colorectal tumors. There are no specific diagnostic or therapeutic recommended approaches and most of the information available from literature derives from small and retrospective clinical series. In the present study, we provide a paramount and updated view on clinical and biologic characteristics of rare colorectal tumors.

• Authors: Alessandro Ottaiano, Mariachiara Santorsola, Francesco Perri, Ugo Pace, Bruno Marra, Marco Correra, Francesco Sabbatino, Marco Cascella, Nadia Petrillo, Monica Ianniello, Marika Casillo, Gabriella Misso, Paolo Delrio, Michele Caraglia, Guglielmo Nasti
• Journal: Biology (Biology (Basel)) Vol. 11 Issue 2 (Feb 08 2022) ISSN: 2079-7737 [Print] Switzerland
• PMID: 35205133 (Publication Type: Journal Article, Review)