Survival outcome of local vs. radical excision in rectal gastrointestinal stromal tumor: a SEER database analysis.

Abstract

BACKGROUND:

The choice of surgical strategy for patients with rectal gastrointestinal stromal tumor (GIST) remains controversial. This study aims to address whether the surgical procedure [local excision (LE) vs. radical excision (RE)] influences the survival outcomes.

METHODS:

The information of the patients recruited in this study was obtained from the Surveillance, Epidemiology, and End Results (SEER) database. A survival curve was used to evaluate the differences in cancer-specific survival (CSS).

RESULTS:

No significant difference was detected in the CSS between the LE and RE groups. Also, no significant differences were observed in the CSS between the two groups with respect to different T classification, N classification, tumor differentiation, tumor size, regional LN surgery, age, gender, race, chemotherapy, and radiotherapy. The T classification and age were independent prognostic factors in rectal GIST patients.

CONCLUSIONS:

LE and RE have similar survival time after surgery, and LE could be considered as an effective surgical approach for rectal GIST.

• Authors: Jianchang Wei, Junbin Zhong, Zhuanpeng Chen, Qing Huang, Fang Wei, Qiang Wang, Jie Cao
• Journal: BMC surgery (BMC Surg) Vol. 22 Issue 1 Pg. 21 (Jan 22 2022) ISSN: 1471-2482 [Electronic] England
• PMID: 35065645 (Publication Type: Journal Article)
• Copyright: © 2022. The Author(s).

Topics

• Databases, Factual
• Digestive System Surgical Procedures
• Gastrointestinal Stromal Tumors (surgery)
• Humans
• Neoplasm Staging
• Rectal Neoplasms (pathology, surgery)
• Rectum (pathology)