Cardiotoxicity and Chemotherapy-The Role of Precision Medicine.

Abstract

Cancer and cardiovascular disease are the leading causes of death in the United Kingdom. Many systemic anticancer treatments are associated with short- and long-term cardiotoxicity. With improving cancer survival and an ageing population, identifying those patients at the greatest risk of cardiotoxicity from their cancer treatment is becoming a research priority and has led to a new subspecialty: cardio-oncology. In this concise review article, we discuss cardiotoxicity and systemic anticancer therapy, with a focus on chemotherapy. We also discuss the challenge of identifying those at risk and the role of precision medicine as we strive for a personalised approach to this clinical scenario.

• Authors: Thyla Viswanathan, Chim C Lang, Russell D Petty, Mark A Baxter
• Journal: Diseases (Basel, Switzerland) (Diseases) Vol. 9 Issue 4 (Dec 08 2021) ISSN: 2079-9721 [Print] Switzerland
• PMID: 34940028 (Publication Type: Journal Article, Review)