High-flow arteriovenous fistula and hemodynamic consequences at 1 year after kidney transplantation.

Abstract

INTRODUCTION:

There are only scarce data regarding the cardiovascular impact of arteriovenous fistula after kidney transplantation depending on fistula flow.

METHODS:

We performed a single-center, prospective, cohort study including 49 patients with a functional fistula at 1 year from kidney transplantation. Patients were convened for a clinical work-up, a biological analysis, a fistula's Doppler ultrasonography and an echocardiography. Main judgment criterion was comparison of echocardiography parameters between patients with relative (fistula flow >1 L/min and a fistula flow/cardiac output ratio >20%), absolute high-flow fistula (fistula flow >2 L/min) and normal-flow fistula.

RESULTS:

High-flow fistula frequency was 69%. Significantly higher left ventricular end-diastolic and systolic diameters were observed in this group compared with the normal-flow fistula group (53 ± 6 vs. 48 ± 7 mm; p = 0.04 and 33 ± 6 vs. 28 ± 8 mm; p = 0.02) and between the absolute and relative high-flow fistula subgroups (56 ± 6 vs. 51 ± 6 mm; p = 0.009 and 35 ± 6 vs. 31 ± 5 mm; p = 0.01). The study showed no other significant differences.

CONCLUSIONS:

This study showed a significantly higher but not pathological left ventricular end-diastolic and systolic diameters values in patients with high-flow fistula compared with patients with normal-flow fistula and between patients with respectively absolute and relative high-flow fistula.

• Authors: Nicolas Keller, Alexandra Monnier, Sophie Caillard, Noëlle Cognard, Bernard Geny, Bruno Moulin, Samy Talha
• Journal: Seminars in dialysis (Semin Dial) Vol. 35 Issue 2 Pg. 171-180 (03 2022) ISSN: 1525-139X [Electronic] United States
• PMID: 34726295 (Publication Type: Journal Article)
• Copyright: © 2021 Wiley Periodicals LLC.

Topics

• Arteriovenous Fistula (diagnostic imaging, etiology)
• Arteriovenous Shunt, Surgical (adverse effects)
• Cohort Studies
• Hemodynamics
• Humans
• Kidney Transplantation (adverse effects)
• Prospective Studies
• Renal Dialysis (adverse effects)