Source of elevated serum mitochondrial creatine kinase activity in patients with malignancy.

Abstract	Mitochondrial creatine kinase (CK-mit) is increased in cancer tissues of the digestive tract. There is no difference in molecular weight, electrophoretic and kinetic properties between the isoenzymes extracted from the tumor and those from the adjacent normal tissues. High non-CK-M/total CK activity ratios in some sera from cancer patients probably reflect leakage of CK-mit from the tumor tissues.
Authors	K Okano, K Yamamoto, Y Ohba, K Matsumura, T Miyaji
Journal	Clinica chimica acta; international journal of clinical chemistry (Clin Chim Acta) Vol. 169 Issue 2-3 Pg. 159-63 (Nov 16 1987) ISSN: 0009-8981 [Print] Netherlands
PMID	3427777 (Publication Type: Journal Article)
Chemical References	Isoenzymes Creatine Kinase
Topics	Adult Aged Aged, 80 and over Chromatography, Ion Exchange Creatine Kinase (blood) Electrophoresis, Agar Gel Female Humans Isoenzymes Male Middle Aged Neoplasms (enzymology)

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