Abstract | PURPOSE: PATIENTS AND METHODS: Eligible LBC patients diagnosed between 2011 and 2013 were identified via the Taiwan Cancer Registry. We used propensity score (PS) weighting to balance observable potential confounders between groups. The hazard ratio (HR) of death and other outcomes were compared between IGRT and non-IGRT. We also evaluated OS in various supplementary analyses. RESULTS: Our primary analysis included 6490 patients in whom covariates were well balanced after PS weighing. The HR for death when IGRT was compared with non-IGRT was 1.02 (95% confidence interval 0.80-1.31, P = 0.86). There were also no significant differences in the supplementary analyses. CONCLUSION: We found that OS of LBC patients treated with adjuvant CFRT was not statistically different between those treated with IGRT versus without IGRT. This was the first study in this regard to our knowledge but randomized controlled trials were needed to confirm our finding.
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Authors | Ji-An Liang, Po-Chang Lee, Chun-Ping Ku, William Tzu-Liang Chen, Chih-Yuan Chung, Yu-Cheng Kuo, Szu-Hsien Chou, Chia-Chin Li, Chun-Ru Chien |
Journal | Cancer management and research
(Cancer Manag Res)
Vol. 13
Pg. 3465-3472
( 2021)
ISSN: 1179-1322 [Print] New Zealand |
PMID | 33907469
(Publication Type: Journal Article)
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Copyright | © 2021 Liang et al. |