Laser interstitial thermal therapy for gyrus rectus cortical dysplasia in a child: a technical note.

Abstract

Laser interstitial thermal therapy (LITT) has become a popular tool in the treatment of tumors and epilepsy. While most commonly used for the treatment of mesial temporal lobe epilepsy, it can be used as a minimally invasive option for the treatment of any seizure focus but has very rarely been discussed in the setting of cortical dysplasia. Here, we discuss the case of a 5-year-old girl with medically refractory epilepsy secondary to a right medial orbital gyrus and gyrus rectus cortical dysplasia successfully treated with LITT. After confirmation of seizure focus using stereo electroencephalography (SEEG), the patient underwent thermal ablation of the focus through an eyebrow incision with use of a single laser fiber. She has been seizure-free 6 months postoperatively, only on one anti-seizure medication, with normal EEG. The use of LITT in this case was successful because of the cylindrical shape of the cortical dysplasia, making it easily accessible via a single laser fiber in the absence of a yet to develop fontal sinus. While open resection would have also been appropriate, the use of LITT provided a minimally invasive alternative approach that allowed for an excellent outcome with limited risks.

• Authors: Rachel Pruitt, David Bonda, Shefali Kakare, Sanjeev Kothare, Shaun Rodgers
• Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery (Childs Nerv Syst) Vol. 37 Issue 5 Pg. 1747-1751 (05 2021) ISSN: 1433-0350 [Electronic] Germany
• PMID: 33825977 (Publication Type: Case Reports, Journal Article)

Topics

• Child
• Child, Preschool
• Drug Resistant Epilepsy (surgery)
• Epilepsy, Temporal Lobe (surgery)
• Female
• Humans
• Laser Therapy
• Lasers
• Magnetic Resonance Imaging
• Malformations of Cortical Development (complications, diagnostic imaging, surgery)
• Prefrontal Cortex
• Treatment Outcome