Abstract | OBJECTIVE: In December 2019, Wuhan, China, experienced an outbreak of coronavirus disease 2019 (COVID-19). Some patients admitted to our hospital were treated with early prone positioning (PP). Here, we analyzed its clinical significance. METHODS: This was a retrospective observational study. We defined the early PP group as mild COVID-19 patients who were placed into a prone position within 24h of admission; others served as the control group. We recorded basic data and outcomes of early PP and compared the results to those of controls. RESULTS: After 1 day of treatment, oxygenation was greater in the early PP group than in the control group (P/F: 421.6±39.74 vs. 382.1±38.84mmHg [1mmHg=0.133kPa], p<0.01). And early PP group spent less total time in prone position (11.1±4.17 vs. 16.9±5.20 days, p<0.01), and required shorter hospitalization duration (12.2±4.49 vs. 23.2±4.83 days, p<0.001). CONCLUSIONS: Early PP treatment can improve hypoxia and shorten the prone position time and hospitalization duration in mild COVID-19 patients. It is a potential clinically applicable intervention.
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Authors | Xiaoyi Liu, Hui Liu, Qing Lan, Xiangde Zheng, Jun Duan, Fanwei Zeng |
Journal | Medicina clinica
(Med Clin (Barc))
Vol. 156
Issue 8
Pg. 386-389
(04 23 2021)
ISSN: 1578-8989 [Electronic] Spain |
PMID | 33478810
(Publication Type: Journal Article, Observational Study)
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Copyright | Copyright © 2020 Elsevier España, S.L.U. All rights reserved. |
Topics |
- Adult
- COVID-19
(therapy)
- China
(epidemiology)
- Female
- Humans
- Male
- Middle Aged
- Patient Positioning
- Prone Position
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