Proximal versus total gastrectomy for proximal gastric cancer: a Surveillance, Epidemiology, and End Results Program database analysis.

Abstract

Aims: To addresses whether surgical procedure (proximal gastrectomy [PG] vs total gastrectomy [TG]) influences survival outcomes. Methods: Patients were selected from Surveillance, Epidemiology and End Results Program (SEER) database. Survival curve was used to evaluate the differences in overall survival (OS) and cancer-specific survival (CSS). Results: No significant difference was detected in OS and CSS time between PG and TG groups. Also, no significant differences were observed in OS and CSS times between the two groups with respect to clinical stage, tumor stage, node stage, age, gender and tumor differentiation. Tumor differentiation, tumor size, tumor stage, node stage and age were independent prognostic factors in patients with proximal gastric cancer. Conclusions: TG was not necessary for proximal gastric cancer patients, and PG may be considered as an ideal surgery approach.

• Authors: Jianchang Wei, Ping Yang, Qing Huang, Zhuanpeng Chen, Tong Zhang, Feng He, He Hu, Junbin Zhong, Wanglin Li, Fang Wei, Qiang Wang, Jie Cao
• Journal: Future oncology (London, England) (Future Oncol) Vol. 17 Issue 10 Pg. 1185-1195 (Apr 2021) ISSN: 1744-8301 [Electronic] England
• PMID: 33289395 (Publication Type: Journal Article)

Topics

• Disease Management
• Female
• Gastrectomy (methods)
• Health Care Surveys
• Humans
• Male
• Prognosis
• SEER Program
• Stomach Neoplasms (epidemiology, pathology, surgery)
• Treatment Outcome