Abstract | BACKGROUND: The nutritional determinants of stroke and, more specifically, the association of frying with the risk of incident stroke have rarely been studied. OBJECTIVES: Our aim was to evaluate prospectively the association between the consumption of fried food and the risk of incident stroke in the European Prospective Investigation into Cancer and Nutrition study using the Spanish cohort. METHODS: Participants included 40,328 healthy adults (62% women) aged 29-69 y at study entry who were enrolled between 1992 and 1996. Participants were followed up until 31 December, 2017, at which time incident stroke (the main outcome) was measured. The main exposure measure was the percentage of energy obtained from fried-food consumption. Sex-specific quintiles were calculated. RESULTS: During a follow-up period of 23.5 y, 975 cases of stroke occurred (750 ischemic, 185 hemorrhagic, and 40 undetermined). Compared with those in the first (lowest) quintile of fried-food consumption, the multivariate HRs (95% CIs) of incident stroke in the consecutive quintiles were 1.05 (0.86, 1.30), 1.11 (0.90, 1.36), 1.05 (0.84, 1.31), and 0.91 (0.72, 1.15; P-trend = 0.45). There were no differences identified when subtypes of stroke were considered. CONCLUSIONS: In this Spanish cohort, whose participants mainly used olive oil or sunflower oil when frying, the consumption of fried food was not associated with an increased risk of incident stroke.
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Authors | Jimena Rey-García, Pilar Guallar-Castillón, Carolina Donat-Vargas, Conchi Moreno-Iribas, Aurelio Barricarte, Miguel Rodriguez-Barranco, Sandra Colorado-Yohar, José-María Huerta, María-Dolores Chirlaque, Cristina Lasheras, Pilar Amiano, Liher Imaz, Antonio Agudo, María-José Sánchez |
Journal | The Journal of nutrition
(J Nutr)
Vol. 150
Issue 12
Pg. 3241-3248
(12 10 2020)
ISSN: 1541-6100 [Electronic] United States |
PMID | 32939531
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | © The Author(s) 2020. Published by Oxford University Press on behalf of the American Society for Nutrition. |
Chemical References |
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Topics |
- Adult
- Aged
- Cohort Studies
- Cooking
- Female
- Humans
- Male
- Middle Aged
- Nutrition Assessment
- Nutrition Surveys
- Olive Oil
- Prospective Studies
- Risk Factors
- Spain
- Stroke
(etiology)
- Sunflower Oil
- Surveys and Questionnaires
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