Diagnostic value of radionuclide in bone metastasis after breast cancer surgery: A protocol of systematic review.

Abstract

BACKGROUND:

The objective of this study is to evaluate the accuracy of radionuclide in diagnosis of bone metastasis (BM) after breast cancer surgery (BCS).

METHODS:

The electronic databases (Cochrane Library, MEDLINE, EMBASE, Web of Science, CBM, and CNKI) will be systematically and comprehensively searched until June 1, 2020 for eligible studies that reported the diagnosis of radionuclide in BM after BCS. In addition, we will also identify grey literatures, such as conference abstracts, and reference lists of included studies. All process of study identification, data extraction, and study methodological quality evaluation will be performed by 2 independent authors. All divergences will be settled by a third author through discussion. All data analysis will be carried out by RevMan 5.3 software (London, UK).

RESULTS:

This study will scrutinize the most recent evidence of radionuclide in detection of BM after BCS.

CONCLUSION:

This study may provide evidence of accuracy of radionuclide in diagnosis of BM following BCS.

STUDY REGISTRATION NUMBER:

PROSPERO CRD42020187646.

• Authors: Qi-Xin Lian, Wei Zhao, Gang Li, Lian-Jin Jin, Hao-Jie Nie
• Journal: Medicine (Medicine (Baltimore)) Vol. 99 Issue 33 Pg. e21585 (Aug 14 2020) ISSN: 1536-5964 [Electronic] United States
• PMID: 32872010 (Publication Type: Journal Article, Systematic Review)

Topics

• Age Factors
• Bone Neoplasms (diagnosis, secondary)
• Breast Neoplasms (pathology, surgery)
• Diagnostic Errors
• Diagnostic Techniques, Radioisotope
• Female
• Humans
• Research Design
• Sensitivity and Specificity
• Socioeconomic Factors