Using Polyethylene Glycol 3350 Plus Electrolytes in Constipated Hemodialysis Patients: A Case Series.

Abstract

Appropriate management of constipation in hemodialysis patients has not been established, although constipation is the most frequent gastrointestinal complication in dialysis patients. We herein report the efficacy and safety of polyethylene glycol in constipated hemodialysis patients assessed prospectively. Seven patients using stimulant laxatives participated in this study. Polyethylene glycol was administered to reduce stimulant laxatives during the six-week intervention period. The amount of stimulant laxatives decreased and spontaneous bowel movements with ideal stool consistency increased significantly after the intervention. No serious adverse effects were observed throughout this study. In conclusion, polyethylene glycol can be a useful tool for managing constipated hemodialysis patients.

• Authors: Hiroyuki Endo, Noriyuki Obara, Takashi Watanabe, Satoru Sanada, Tomoyuki Koike, Atsushi Masamune
• Journal: Internal medicine (Tokyo, Japan) (Intern Med) Vol. 60 Issue 3 Pg. 379-384 (Feb 01 2021) ISSN: 1349-7235 [Electronic] Japan
• PMID: 32863362 (Publication Type: Case Reports, Journal Article)

Chemical References

• Electrolytes
• Laxatives
• Polyethylene Glycols
• polyethylene glycol 3350

Topics

• Constipation (drug therapy)
• Electrolytes (therapeutic use)
• Humans
• Laxatives (therapeutic use)
• Polyethylene Glycols (adverse effects)
• Renal Dialysis (adverse effects)
• Treatment Outcome