Diagnosis and Treatment of Bone Metastases in Breast Cancer: Radiotherapy, Local Approach and Systemic Therapy in a Guide for Clinicians.

Abstract

The standard care for metastatic breast cancer (MBC) is systemic therapies with imbrication of focal treatment for symptoms. Recently, thanks to implementation of radiological and metabolic exams and development of new target therapies, oligometastatic and oligoprogressive settings are even more common-paving the way to a paradigm change of focal treatments role. In fact, according to immunophenotype, radiotherapy can be considered with radical intent in these settings of patients. The aim of this literature review is to analyze available clinical data on prognosis of bone metastases from breast cancer and benefits of available treatments for developing a practical guide for clinicians.

• Authors: Fabio Marazzi, Armando Orlandi, Stefania Manfrida, Valeria Masiello, Alba Di Leone, Mariangela Massaccesi, Francesca Moschella, Gianluca Franceschini, Emilio Bria, Maria Antonietta Gambacorta, Riccardo Masetti, Giampaolo Tortora, Vincenzo Valentini
• Journal: Cancers (Cancers (Basel)) Vol. 12 Issue 9 (Aug 24 2020) ISSN: 2072-6694 [Print] Switzerland
• PMID: 32846945 (Publication Type: Journal Article, Review)