HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Suicidal thinking and behaviours in First Episode Psychosis: Findings from a 3-year longitudinal study.

AbstractAIM:
Suicide risk is greater at the beginning of the course of psychosis. Purpose of this research was: (a) to investigate prevalence and incidence rates of suicide attempts, suicidal thinking and completed suicide in First Episode Psychosis (FEP) help-seekers as compared with non-FEP help-seeking peers, and (b) to examine any correlation of suicidal ideation with other baseline psychopathological predictors.
METHODS:
Two hundred and forty-one young people (13-35 years) were assessed with the World Health Organization Quality Of Life scale - Brief version (WHOQOL-BREF), the Beck Depression Inventory - II Edition (BDI-II) and the Comprehensive Assessment of At-Risk Mental States (CAARMS) at the enrollment and over a 36-month follow-up period. A Kaplan-Meier survival analysis to calculate cumulative incidence rates of attempted and completed suicide was used.
RESULTS:
FEP patients showed more severe levels of CAARMS "Suicidality/Self-Harm" item than non-FEP peers. They also had higher 3-year incidence rates of attempted suicide (11%) and completed suicide (13%). Within the FEP total group, suicidal ideation was positively correlated with BDI-II and CAARMS "Perceptual Abnormalities" item scores, and showed negative associations with younger age and WHOQOL-BREF "Social Relationships" factor sub-score.
CONCLUSIONS:
Suicidal ideation is relevant in FEP patents, supporting the routine monitoring of suicide risk in baseline assessment of adolescents and young adults with early psychosis. Suicidal thinking seems to be correlated to younger age, perceptual aberrations and depression severity, as well as to poorer quality of social relationships.
AuthorsLorenzo Pelizza, Maurizio Pompili, Silvia Azzali, Federica Paterlini, Sara Garlassi, Ilaria Scazza, Luigi Rocco Chiri, Michele Poletti, Simona Pupo, Andrea Raballo
JournalEarly intervention in psychiatry (Early Interv Psychiatry) Vol. 15 Issue 3 Pg. 624-633 (06 2021) ISSN: 1751-7893 [Electronic] Australia
PMID32462776 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Copyright© 2020 John Wiley & Sons Australia, Ltd.
Topics
  • Adolescent
  • Humans
  • Longitudinal Studies
  • Psychotic Disorders (epidemiology)
  • Quality of Life
  • Risk Factors
  • Suicidal Ideation
  • Suicide, Attempted
  • Young Adult

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: