Ibex-Associated Malignant Catarrhal Fever in Duikers (Cephalophus Spp).

Abstract

Eight duikers, representing 3 different species cohoused in a single zoological collection, died in a 10-month period. Black, red-flanked, and yellow-backed duikers were affected, appearing clinically with a combination of anorexia, diarrhea, ataxia, tremors, and/or stupor, followed by death within 72 hours of onset of clinical signs. Consistent gross findings were pulmonary ecchymoses (8/8), generalized lymphadenomegaly (6/8), ascites (5/8), and pleural effusion (4/8). Dense lymphocyte infiltrates and arteritis affected numerous tissues in most animals. Ibex-associated malignant catarrhal fever (MCF) viral DNA was detected in all cases by polymerase chain reaction and in situ hybridization. Identical ibex-MCF virus sequence was detected in spleen of a clinically healthy ibex (Capra ibex) housed in a separate enclosure 35 meters away from the duikers.

• Authors: Francisco R Carvallo, Francisco A Uzal, Janet D Moore, Kenneth Jackson, Akinyi C Nyaoke, Lisa Naples, Jordan Davis-Powell, Cynthia K Stadler, Brandon A Boren, Cristina Cunha, Hong Li, Patricia A Pesavento
• Journal: Veterinary pathology (Vet Pathol) Vol. 57 Issue 4 Pg. 577-581 (07 2020) ISSN: 1544-2217 [Electronic] United States
• PMID: 32406327 (Publication Type: Case Reports, Journal Article)

Chemical References

• Alcelaphine gammaherpesvirus 1
• DNA, Viral

Topics

• Animals
• Animals, Wild (virology)
• Animals, Zoo (virology)
• Antelopes (virology)
• California
• Cattle
• Cattle Diseases (pathology, virology)
• DNA, Viral (genetics)
• Gammaherpesvirinae (genetics, isolation & purification)
• Goats (virology)
• Herpesviridae (genetics, isolation & purification)
• Herpesviridae Infections (pathology, transmission, veterinary)
• In Situ Hybridization (veterinary)
• Kidney (pathology)
• Lung (pathology)
• Male
• Malignant Catarrh (pathology, transmission, virology)
• Polymerase Chain Reaction (veterinary)
• Ruminants (virology)
• Testis (pathology)
• Urinary Bladder (pathology)