Enteropathy-associated T-cell Lymphoma (EATL) with intracranial metastasis : a rare and dismal condition.

Abstract

BACKGROUND:

Enteropathy-associated T-cell lymphoma (EATL) is a rare type of gastrointestinal non-Hodgkin's Lymphoma. EATL with intracranial metastasis is even rarer. We report a case of EATL with intracranial metastasis.

CASE PRESENTATION:

A 36-years old man presented with five weeks history of intractable diarrhea. Colonoscopy was normal, but abdominal computed tomography (CT) scan revealed mural thickening at duodenojejunal junction, and subsequent jejunofiberoscopy showed a circumferential ulceration at the jejunum. Histo-immunopathology confirmed the diagnosis of enteropathyassociated T-cell lymphoma (EATL) type II. His disease course proved to be aggressive and refractory to standard front-line chemotherapy, and eventually progressed through second-line salvage regimen with CNS and intracranial involvement. He died nine months after the initial diagnosis.

CONCLUSION:

EATL with brain metastasis is a very rare occurrence with dismal prognosis.

• Authors: Y Y Chuah, T Tashi, Y Y Lee, T Y Fu, C A Shih
• Journal: Acta gastro-enterologica Belgica (Acta Gastroenterol Belg) 2020 Jan-Mar Vol. 83 Issue 1 Pg. 77-80 ISSN: 1784-3227 [Print] Belgium
• PMID: 32233276 (Publication Type: Case Reports)
• Copyright: © Acta Gastro-Enterologica Belgica.

Topics

• Adult
• Colonoscopy
• Diarrhea
• Enteropathy-Associated T-Cell Lymphoma
• Gastrointestinal Neoplasms
• Humans
• Male
• Prognosis