Can robotic-assisted radical cystectomy provide patients with a smaller trauma and faster recovery period? A systematic review and meta-analysis of comparative trials.

Abstract

OBJECTIVE:

This article explores the differences in the effectiveness and safety of the treatment of bladder cancer (BC) by robotic-assisted radical cystectomy (RARC) and laparoscopic radical cystectomy (LRC).

METHODS:

A systematic search was performed using databases including Medline, PubMed and Web of Science within a limited period from January 1, 2000, to September 1, 2019. RevMan 5.3 was used for calculation and statistical analyses.

RESULTS:

We performed meta-analysis on operation time, estimated blood loss, intraoperative blood transfusion, positive surgical margin, oral intake time, length of hospital stay, complication and other indicators, and found that there were no statistically significant differences between LRC and RARC.

CONCLUSION:

Our meta-analysis results show that LRC and RARC have similar results on the effectiveness and safety of BC. For those medical institutions that cannot perform robot-assisted surgery but are seeking minimally invasive and faster postoperative recovery, LRC is worth considering. However, a larger sample size, more rigorous design and longer follow-up randomized controlled trials are still needed to support our conclusions.

• Authors: Lei Peng, Jinze Li, Dehong Cao, Zhengju Ren, Tangqiang Wei, Chengyu You, Bo Cheng, Qiang Wei, Yunxiang Li
• Journal: Journal of cancer research and clinical oncology (J Cancer Res Clin Oncol) Vol. 146 Issue 6 Pg. 1591-1601 (Jun 2020) ISSN: 1432-1335 [Electronic] Germany
• PMID: 32185487 (Publication Type: Journal Article, Meta-Analysis, Systematic Review)

Topics

• Cystectomy (methods, rehabilitation)
• Humans
• Robotic Surgical Procedures (methods)
• Urinary Bladder Neoplasms (surgery)