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Durable response with single-agent acalabrutinib in patients with relapsed or refractory mantle cell lymphoma.

AuthorsMichael Wang, Simon Rule, Pier Luigi Zinzani, Andre Goy, Olivier Casasnovas, Stephen D Smith, Gandhi Damaj, Jeanette K Doorduijn, Thierry Lamy, Franck Morschhauser, Carlos Panizo, Bijal Shah, Andrew Davies, Richard Eek, Jehan Dupuis, Eric Jacobsen, Arnon P Kater, Steven Le Gouill, Lucie Oberic, Tadeusz Robak, Preetesh Jain, Melanie M Frigault, Raquel Izumi, Dorothy Nguyen, Priti Patel, Ming Yin, Monika Długosz-Danecka
JournalLeukemia (Leukemia) Vol. 33 Issue 11 Pg. 2762-2766 (11 2019) ISSN: 1476-5551 [Electronic] England
PMID31558766 (Publication Type: Clinical Trial, Phase II, Letter, Multicenter Study, Research Support, Non-U.S. Gov't)
Chemical References
  • Antineoplastic Agents
  • Benzamides
  • Ki-67 Antigen
  • Pyrazines
  • Agammaglobulinaemia Tyrosine Kinase
  • BTK protein, human
  • acalabrutinib
Topics
  • Adult
  • Agammaglobulinaemia Tyrosine Kinase (antagonists & inhibitors)
  • Aged
  • Aged, 80 and over
  • Antineoplastic Agents (therapeutic use)
  • Benzamides (therapeutic use)
  • Cell Proliferation
  • Disease Progression
  • Drug Resistance, Neoplasm
  • Female
  • Follow-Up Studies
  • Humans
  • Ki-67 Antigen (metabolism)
  • Lymphoma, Mantle-Cell (drug therapy)
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local (drug therapy)
  • Neoplasm, Residual
  • Pyrazines (therapeutic use)
  • Time Factors
  • Treatment Outcome

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