Maternal and neonatal responses to alfentanil administered before induction of general anaesthesia for caesarean section.

Abstract

The cardiovascular response to tracheal intubation was compared in two groups of patients undergoing elective Caesarean section. Both groups received a standard technique of general anaesthesia. One of the groups received alfentanil 10 micrograms kg-1 1 min before induction of anaesthesia, the other acted as a control group. In the alfentanil group there was a significant modification of the cardiovascular response to intubation as compared with the control group (P less than 0.01). No adverse effect on the neonate was seen. However, a significant increase in the incidence of postoperative nausea occurred in mothers in the alfentanil group (P less than 0.05).

• Authors: W L Dann, A Hutchinson, D P Cartwright
• Journal: British journal of anaesthesia (Br J Anaesth) Vol. 59 Issue 11 Pg. 1392-6 (Nov 1987) ISSN: 0007-0912 [Print] England
• PMID: 3120764 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Adjuvants, Anesthesia
• Alfentanil
• Fentanyl

Topics

• Adjuvants, Anesthesia (pharmacology)
• Alfentanil
• Anesthesia, General (adverse effects)
• Anesthesia, Obstetrical (adverse effects)
• Apgar Score
• Cesarean Section
• Female
• Fentanyl (adverse effects, analogs & derivatives, pharmacology)
• Hemodynamics (drug effects)
• Humans
• Infant, Newborn
• Intubation, Intratracheal
• Pregnancy