Abstract | BACKGROUND: AIM: PATIENTS AND METHODS: RESULTS: In the 2-year follow-up, the mortality rate among women was significantly higher compared with men: 39.8 versus 30.9% (P=0.0009) in the TIMI 0 or 1 group, and 31.6 versus 20% (P<0.0001) in the TIMI 2 group. In women, the risk of rehospitalization because of heart failure was significantly higher irrespective of the final TIMI flow grade. In the multivariate analysis, female sex did not influence both in-hospital (odds ratio: 1.09; 95% confidence interval: 0.82-1.44; P=0.54) and long-term (hazard ratio: 1.14; 95% confidence interval: 0.97-1.34; P=0.11) mortality. Peripheral artery disease, anterior myocardial infarction, and previous stroke were associated with increased mortality only in men. Postprocedural TIMI flow grade 2 (vs. TIMI grade 0 or 1) was the strongest factor impacting mortality irrespective of sex. CONCLUSION: Women with STEMI and postprocedural suboptimal epicardial blood flow have higher mortality than men and are at high risk of developing heart failure, with frequent in-patient visits. However, these differences may be attributed to the advanced age and worse clinical presentation of women compared with men.
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Authors | Małgorzata Zachura, Krzysztof Wilczek, Marianna Janion, Mariusz Gąsior, Marek Gierlotka, Marcin Sadowski |
Journal | Coronary artery disease
(Coron Artery Dis)
Vol. 30
Issue 3
Pg. 171-176
(05 2019)
ISSN: 1473-5830 [Electronic] England |
PMID | 30973830
(Publication Type: Comparative Study, Journal Article, Multicenter Study, Observational Study)
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Topics |
- Aged
- Aged, 80 and over
- Coronary Artery Disease
(diagnostic imaging, mortality, physiopathology, therapy)
- Coronary Circulation
- Female
- Health Status Disparities
- Heart Failure
(mortality, physiopathology, therapy)
- Humans
- Incidence
- Male
- Middle Aged
- Patient Readmission
- Percutaneous Coronary Intervention
(adverse effects, mortality)
- Poland
(epidemiology)
- Prevalence
- Registries
- Risk Assessment
- Risk Factors
- ST Elevation Myocardial Infarction
(diagnostic imaging, mortality, physiopathology, therapy)
- Sex Factors
- Time Factors
- Treatment Failure
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