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Pegylated Bovine Carboxyhemoglobin (SANGUINATE) in a Jehovah's Witness Undergoing Liver Transplant: A Case Report.

Abstract
Liver transplantation in practicing Jehovah's Witnesses is challenging because of their religious beliefs preventing them from accepting allogenic blood products. Pegylated bovine carboxyhemoglobin (SANGUINATE) is an oxygen transfer agent, currently under investigation for the treatment of sickle cell disease, which may play a role in these patients by maximizing perioperative oxygen delivery. We report a case involving the use of SANGUINATE in a Jehovah's Witness undergoing liver transplant.
AuthorsM L Holzner, S DeMaria, B Haydel, N Smith, D Flaherty, S Florman
JournalTransplantation proceedings (Transplant Proc) Vol. 50 Issue 10 Pg. 4012-4014 (Dec 2018) ISSN: 1873-2623 [Electronic] United States
PMID30577305 (Publication Type: Case Reports, Journal Article)
CopyrightCopyright © 2018 Elsevier Inc. All rights reserved.
Chemical References
  • Blood Substitutes
  • Carboxyhemoglobin
Topics
  • Animals
  • Blood Substitutes (therapeutic use)
  • Carboxyhemoglobin (therapeutic use)
  • Cattle
  • Female
  • Humans
  • Jehovah's Witnesses
  • Liver Transplantation (methods)
  • Middle Aged

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